UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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SCHEDULE 13D

 

Under the Securities Exchange Act of 1934

 

(Amendment No. ___)*

 

Wave Life Sciences Ltd.
(Name of Issuer)
 
Ordinary Shares
(Title of Class of Securities)
 
Y95308105
(CUSIP Number)

 

RA Capital Management, LLC
20 Park Plaza, Suite 1200
Boston, MA 02116
Telephone: 617.778.2512
Attn: Peter Kolchinsky
(Name, Address and Telephone Number of Person Authorized to
Receive Notices and Communications)

 

November 16, 2015
(Date of Event Which Requires Filing of this Statement)

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ¨

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

CUSIP No. Y95308105

 

1

Names of Reporting Persons.

 

RA Capital Management, LLC

 

2 Check the Appropriate Box if a Member of a Group (See Instructions)
  (a)         ¨
  (b)         ¨
3 SEC Use Only
4

Source of Funds (See Instructions):

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):

¨

6

Citizenship or Place of Organization.     Massachusetts

 

Number

of Shares

Beneficially

Owned by

Each

Reporting

Person With

7          Sole Voting Power     0 shares

 

8          Shared Voting Power     7,088,651 shares

 

9          Sole Dispositive Power     0 shares

 

10        Shared Dispositive Power     7,088,651 shares

 

11

Aggregate Amount Beneficially Owned by Each Reporting Person

7,088,651 shares

 

12 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)     ¨
13

Percent of Class Represented by Amount in Row (11)

33.9%

 

14

Type of Reporting Person (See Instructions)

IA, OO (Limited Liability Company)

 

 

 

 

 

 

CUSIP No. Y95308105

 

1

Names of Reporting Persons.

 

RA Capital Healthcare Fund, L.P.

 

2 Check the Appropriate Box if a Member of a Group (See Instructions)
  (a)         ¨
  (b)         ¨
3 SEC Use Only
4

Source of Funds (See Instructions):

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):

¨

6

Citizenship or Place of Organization.     Delaware

 

Number

of Shares

Beneficially

Owned by

Each

Reporting

Person With

7          Sole Voting Power     0 shares

 

8          Shared Voting Power     6,582,428 shares

 

9          Sole Dispositive Power     0 shares

 

10        Shared Dispositive Power     6,582,428 shares

 

11

Aggregate Amount Beneficially Owned by Each Reporting Person

6,582,428 shares

 

12 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)     ¨
13

Percent of Class Represented by Amount in Row (11)

31.4%

 

14

Type of Reporting Person (See Instructions)

PN (Limited Partnership)

 

 

 

 

 

CUSIP No. Y95308105

 

1

Names of Reporting Persons.

 

Peter Kolchinsky

 

2 Check the Appropriate Box if a Member of a Group (See Instructions)
  (a)         ¨
  (b)         ¨
3 SEC Use Only
4

Source of Funds (See Instructions):

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):

¨

6

Citizenship or Place of Organization.     United States

 

Number

of Shares

Beneficially

Owned by

Each

Reporting

Person With

7          Sole Voting Power     0 shares

 

8          Shared Voting Power     7,088,651 shares

 

9          Sole Dispositive Power     0 shares

 

10        Shared Dispositive Power     7,088,651 shares

 

11

Aggregate Amount Beneficially Owned by Each Reporting Person

7,088,651 shares

 

12 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)     ¨
13

Percent of Class Represented by Amount in Row (11)

33.9%

 

14

Type of Reporting Person (See Instructions)

HC, IN

 

 

 

 

 

 

 

CUSIP No. Y95308105

 

SCHEDULE 13D

 

Item 1. Security and Issuer

 

This Schedule 13D relates to Ordinary Shares (the “Ordinary Shares”), of Wave Life Sciences Ltd., a Singapore public limited company (the “Issuer”).  The address of the principal executive offices of the Issuer is: 8 Cross Street #10-00, PWC Building, Singapore 048424.

 

Item 2. Identity and Background

 

(a) This Schedule 13D is being filed on behalf of (i) RA Capital Healthcare Fund, L.P. (the “Fund”), (ii) Peter Kolchinsky, and (iii) RA Capital Management, LLC (“RA Capital” and together with each of the foregoing, the “Reporting Persons”).

 

Ordinary Shares reported herein for the Fund represent shares beneficially owned and held of record by the Fund. Ordinary Shares reported herein for RA Capital represent shares reported for the Fund as well as shares held in a separately managed account (the “Account”). RA Capital is the general partner of the Fund and serves as investment adviser for the Account. Peter Kolchinsky is the manager of RA Capital. As the investment adviser to the Fund and the Account, RA Capital may be deemed a beneficial owner, for purposes of Section 13(d) of the Securities Exchange Act of 1934 (the “Act”), of any securities of the Issuer owned by the Fund or the Account. As the manager of RA Capital, Mr. Kolchinsky may be deemed a beneficial owner, for purposes of Section 13(d) of the Act, of any securities of the Issuer beneficially owned by RA Capital. RA Capital is a registered investment adviser within the meaning of Rule 13d-1(b)(1)(ii)(E) and Rule 16a-1(a)(v), and Mr. Kolchinsky is a parent or control person of RA Capital within the meaning of Rule 13d-1(b)(1)(ii)(G) and Rule 16a-1(a)(1)(vii). RA Capital and Mr. Kolchinsky disclaim beneficial ownership of the securities reported in this Schedule 13D Statement (the “Statement”) other than for the purpose of determining their obligations under Section 13(d) of the Act, and neither the filing of the Statement nor the filing of this Amendment shall not be deemed an admission that either RA Capital or Mr. Kolchinsky is or was the beneficial owner of such securities for any other purpose.

 

(b) The business address of each of the Reporting Persons is: 20 Park Plaza, Suite 1200, Boston, MA 02116.

 

(c) The Fund is a private investment vehicle. RA Capital provides investment management services to the Fund and the Account. The principal occupation of Mr. Kolchinsky is investment management.

 

(d) None of the Reporting Persons has, during the last five years, been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).

 

(e) None of the Reporting Persons has, during the last five years, been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

 

(f) See Item 6 of the cover pages.

 

 

 

 

CUSIP No. Y95308105

 

Item 3. Source and Amount of Funds or Other Consideration

 

The Reporting Persons acquired the Ordinary Shares reported herein in, in part, in a private placement on January 12, 2015 directly from the Issuer and, in part, upon consummation of the Issuer’s initial public offering. 1,172,060 Ordinary Shares were acquired upon conversion of Series B Preferred shares acquired in a private placement by the Issuer on August 14, 2015, and the remaining shares were acquired for cash from the underwriters of the initial public offering. All purchases of the Series B preferred shares and Ordinary Shares were funded by working capital of the Fund and the Account.

 

Item 4. Purpose of Transaction

 

The Reporting Persons acquired the Ordinary Shares reported herein for investment purposes and not with an intent, purpose or effect of changing control of the Issuer. Although the Reporting Persons currently have no plan or proposal to acquire any additional Ordinary Shares or to dispose of any of the Ordinary Shares reported herein, the Reporting Persons may acquire additional Ordinary Shares from time to time of dispose of Ordinary Shares they beneficially own, consistent with their investment purposes and in amounts to be determined by the Reporting Persons based upon a number of factors, including, without limitation, their ongoing assessment of the Issuer's business prospects, prevailing market conditions, the availability of other investment opportunities, and/or other considerations.

 

In addition, consistent with their investment purpose, the Reporting Persons may engage in communications with persons associated with the Issuer, including shareholders of the Issuer, officers of the Issuer and/or members of the board of directors of the Issuer, to discuss matters regarding the Issuer, including but not limited to its operations and strategic direction. Mr. Kolchinsky currently serves as a director of the issuer and therefore will engage in regular discussions with the Issuer’s board of directors and management as part of his duties as a director.

 

The Reporting Persons have no plans or proposals that relate to, or could result in, any of the matters referred to in paragraphs (a) through (j), inclusive, of the instructions to Item 4 of Schedule 13D.

 

The Reporting Persons may, however, change their purpose and formulate and implement plans or proposals with respect to the Issuer at any time and from time to time. Any such action may be made by the Reporting Persons alone or in conjunction with other shareholders, potential acquirers, financing sources and/or other third parties and could include one or more purposes, plans or proposals that relate to or would result in actions required to be reported herein in accordance with Item 4 of Schedule 13D.

 

Item 5. Interest in Securities of the Issuer

 

(a) and (b) See Items 7-11 of the cover pages and Item 2 above.

 

(c) The following table lists the Reporting Persons’ transactions in Ordinary Shares that were effected during the sixty day period prior to the filing of this Schedule 13D:

 

Transaction   Date   No. Shares   Price
Conversion   16-Nov-2015   970,466* and 201,594   (1)
Purchase   16-Nov-2015   1,570,371* and 304,629   $16.00

 

(1) The Reporting Persons acquired beneficial ownership of the Issuer’s Series B Preferred shares on August 14, 2015, directly from the Issuer in a private placement. The Series B Preferred shares converted automatically into Ordinary Shares upon consummation of the issuer’s initial public offering on November 16, 2015.

 

 

 

 

CUSIP No. Y95308105

 

Shares marked with an * were acquired by the Fund. The remaining shares were acquired for the Account.

 

(d) Not applicable.

 

(e) Not applicable.

 

Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer

 

The Reporting Persons have entered into a standard lock-up agreement with the Issuer and the underwriters of the initial public offering, prohibiting any sale of the Ordinary Shares reported herein during the 180 days following the closing of the offering. The Reporting Persons may be released from lock-up prior to the expiration of the lock-up period at the sole discretion of the underwriters.

 

Item 7. Material to Be Filed as Exhibits

 

Exhibit 1Joint Filing Agreement by and among the Reporting Persons.

 

 

 

 

CUSIP No. Y95308105

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Date:          November 27, 2015

 

  RA CAPITAL HEALTHCARE FUND, L.P.
     
  By: RA Capital Management, LLC
    General Partner
     
  By: /s/ Peter Kolchinsky
  Peter Kolchinsky
  Manager
     
  RA CAPITAL MANAGEMENT, LLC
     
  By: /s/ Peter Kolchinsky
  Peter Kolchinsky
  Manager
     
  PETER KOLCHINSKY
     
  /s/ Peter Kolchinsky

 

 

 

 

CUSIP No. Y95308105

 

Exhibit 1

 

JOINT FILING AGREEMENT

 

This Joint Filing Agreement, dated as of November 27, 2015, is by and among RA Capital Healthcare Fund, L.P., RA Capital Management, LLC, and Peter Kolchinsky (the foregoing are collectively referred to herein as the “Filers”).

 

Each of the Filers may be required to file with the United States Securities and Exchange Commission a statement on Schedule 13G and/or 13D with respect to Ordinary Shares of Wave Life Sciences Ltd. beneficially owned by them from time to time.

 

Pursuant to and in accordance with Rule 13(d)(1)(k) promulgated under the Securities Exchange Act of 1934, as amended, the Filers hereby agree to file a single statement on Schedule 13G and/or 13D (and any amendments thereto) on behalf of each of such parties, and hereby further agree to file this Joint Filing Agreement as an exhibit to such statement, as required by such rule.

 

This Joint Filing Agreement may be terminated by any of the Filers upon one week’s prior written notice or such lesser period of notice as the Filers may mutually agree.

 

Executed and delivered as of the date first above written.

 

  RA CAPITAL HEALTHCARE FUND, L.P.
     
  By: RA Capital Management, LLC
    General Partner
     
  By: /s/ Peter Kolchinsky
  Peter Kolchinsky
  Manager
     
  RA CAPITAL MANAGEMENT, LLC
     
  By: /s/ Peter Kolchinsky
  Peter Kolchinsky
  Manager
   
  PETER KOLCHINSKY
     
  /s/ Peter Kolchinsky